Principal Scientist (Formulation Development)

Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed.

The Opportunity

We’re looking for a Principal Scientist, Formulation Development to lead drug product development from early discovery through late-stage clinical development. You’ll translate promising compounds into robust, phase-appropriate formulations and scalable manufacturing processes, partnering closely with Discovery, CMC, Regulatory, and external development partners.

This role combines deep formulation expertise with hands-on scientific leadership. You’ll shape development strategy, solve complex technical challenges, oversee work at CDMOs, and help move programs forward with urgency and sound judgment. The ideal candidate is technically strong, curious, highly collaborative, and comfortable taking ownership in an agile environment.

Primary Responsibilities

• Lead formulation strategy across programs, representing Formulation/Pharmaceutical Development on CMC and multidisciplinary project teams and clearly communicating strategy, risks, tradeoffs, and recommendations. • Design, oversee, and interpret formulation studies to characterize novel drug candidates, including small molecules and/or ASOs, and translate learnings into development decisions. • Develop phase-appropriate formulations and manufacturing processes using sound formulation, material characterization, and pharmaceutical manufacturing principles. • Partner with Discovery and…